منابع مشابه
Chromosome anomalies among livebirths.
A considerable proportion of heritable disease in man is a consequence of the presence of constitutional chromosome anomalies. We need to distinguish between constitutional anomalies which are present in the germ cell or which arise during the early cleavage divisions of a zygote, so that all, or a substantial proportion, of the cells carry the abnormality, and acquired somatic abnormalities wh...
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The mechanism by which eukaryotic chromosomes condense as cells enter mitosis has long been inaccessible to molecular biologists. An important clue has now been provided by a ubiquitous protein family, the SMCs.
متن کاملB Chromosomes – A Matter of Chromosome Drive
B chromosomes are supernumerary chromosomes which are often preferentially inherited, deviating from usual Mendelian segregation. The balance between the so-called chromosome drive and the negative effects that the presence of Bs applies on the fitness of their host determines the frequency of Bs in a particular population. Drive is the key for understanding most B chromosomes. Drive occurs in ...
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Two new studies show that Aurora B kinase corrects improperly attached chromosomes by recruiting molecules necessary for eliminating the bad attachments and by regulating the turnover of the kinetochore fiber.
متن کاملArchitecture of metaphase chromosomes and chromosome scaffolds
We have developed procedures for depositing intact mitotic chromosomes and isolated residual scaffolds on electron microscope grids at controlled and reproducible levels of compaction. The chromosomes were isolated using a recently developed aqueous method. Our study has addressed two different aspects of chromosome structure. First, we present a method for improved visualization of radial chro...
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ژورنال
عنوان ژورنال: Atlas of Genetics and Cytogenetics in Oncology and Haematology
سال: 2011
ISSN: 1768-3262
DOI: 10.4267/2042/37658